Glossary.

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A

AAV :  Abbr. ANCA-associated vasculitis
ACTH :  Abbr. Adrenocorticotropic Hormone produced in the pituitary gland that stimulates the adrenal glands to release a hormone called cortisol.
ACTH blood test :  [Cosyntropin test, Tetracosactide test, Synacthen test]Test. Helps diagnose problems with the pituitary and adrenal glands by comparing ACTH with cortisol levels.
Adcal :  Med. See Calcium supplements
Accolate :  Med. See Zafirlukast
Adrenocorticotropic Hormone :  Term. See ACTH
Aetiology :  [Etiology] Term. The process or cause that led to a disease or condition.
Alemtuzumab :  [Campath, Lemtrada] Med. Used primarily for leukemia and MS treatment. Trials with EGPA are still at an early stage.
Allergic rhinitis :  [Hay Fever] Term. Inflammation of nasal passages caused by reaction to airborne allergens.
Allergy :  Term. Certain foods or environmental factors cause the body to react adversely. To those affected, the foods or factors are an allergen causing an immune response and creation of antibodies, repeated each time an individual is exposed to that allergen. Symptoms include sneezing, wheezing, itchy eyes, skin rashes and swelling.
Alvesco :  Med. See Ciclesonide
Anaemia :  [Anemia] Cond. Red blood cell count is below normal.
ANA :  Abbr. Test. Antinuclear antibodies. ANA test is used to detect autoantibodies present in blood serum.
ANCA :  Abbr. Term. Anti-Neutrophil Cytoplasmic Antibodies. Group of autoantibodies, mainly IgG type. Present in about 40% of EGPA cases but also occur in other autoimmune conditions. It can be used to support diagnosis.
ANCA Associated Vasculitis :  Term. Vasculitis types characterised by positive ANCA, though some with these conditions (EGPA, GPA and MPA) are ANCA negative.
AntiC1q vasculitis :  Cond. See HUVS
Anti-GBM :  [Anti-Glomerular basement Membrane disease, Goodpasture's disease] Cond.Immune complex, small blood vessel vasculitis. Affects kidneys and lungs.  More
Anti-Glomerular basement Membrane disease :  Cond. See Anti-GBM
Antibody :  [Immunoglobulin] Term. A protein used by the immune system to identify and neutralise agents of disease such as bacteria and viruses.
Antigen :  Term. Foreign substance in the body, for example bacteria and toxins, inducing an immune response causing the production of antibodies which are normally beneficial but can also be harmful.
Arthralgia :  Term.Joint pain.
Ascites :  Cond. Fluid excess between the layers of the peritoneum, a membrane lining the abdomen.
Asthma :  Term. Inflamation of the airways, which can normally be controlled. It has differing degrees of severity involving coughing, wheezing and breathlessness. Having Asthma is a common precursor to EGPA but only around 1 in 100000 asthma sufferers will go on to develop EGPA.
Autoantibody :  Term. An antibody produced by the immune system that destroys healthy cells and tissues, causing inflammation.
Azathioprine :  [Imuran] Med. Immunosuppressive drug. Used for steroid sparing.

B

Barium enema :  [Lower GI series] Test. Uses x-rays to diagnose problems with the large intestine.
Barium meal :  Test. Similar to a barium swallow except looking for the stomach and duodenum problems.
Barium sulphate :  Term. A drink to enhance X-Ray imaging of the gastrointestinal tract.
Barium swallow :  [Upper GI series] Test. Uses a combination of X-rays and fluoroscopy to diagnose problems with the upper gastrointestinal tract.
Baycadron :  Abbr. See Dexamethasone
Behçet's Syndrome :  [Behçet's Disease] Cond.Variable bloodvessel vasculitis. Causes inflammation of the skin, lining of the mouth and genital areas. Other organs and joints can also be painful.  More
Beta agonist :  Med. Bronchodilator drug that widens the bronchi in the lungs to improve airways during an asthma attack.
Biopsy :  Term. A procedure to remove cells or tissue from organs of interest for laboratory analysis.
Brain attack :  Cond.See Stroke
Bronchoscopy :  Term. A procedure using a tube (Bronchoscope) to visually check lung and airways. Can also be used to biopsy lung tissue for more detailed examination.
Buerger's Disease :  [Thromboangiitis obliterans] Cond. Small and medium vessels have clots affecting fingers and toes. Smoking tobacco, is the overwhelming factor.
Bumetanide :  [Bumex] Med. A loop diuretic (water pill) used to treat Oedema
Bumex :  Med. See Bumetanide

C

Calcium supplements :  [Adcal] Med. Used as part of a control plan for steroid induced osteoporosis
Campath :  Med. See Alemtuzumab
Cardiac effusion :  Cond. See Pericardial effusion
Cardiac tamponade :  Cond. See Pericardial tamponade
Cardiologist :  Term. Specialist in cardiology.
Cardiology :  Term. lnvestigation, diagnosis and medical treatment of the heart and blood vessels.
Cardiomegaly :  Cond. Enlarged heart
Cardiothoracic surgeon :  Term. Specialist in cardiac surgery.
Cellcept :  Med. See Mycophenelate mofetil
Central Nervous System Vasculitis :  Cond. See CNS
Cerebral Vasculitis :  Cond. See CNS
Cerebrovascular accident :  Cond. [CVA] See Stroke
Cerebrovascular insult :  Cond. [CVI] See Stroke
Chest Cavity :  Term. See Thoracic cavity
Churg-Strauss Syndrome :  Cond. See EGPA
Ciclesonide :  [Alvesco] Med. Inhaler. Asthma maintenance, corticosteroid.
CKD :  Abbr. Cond. Chronic kidney disease. A condition where the kidneys do not work effectively.
Cinqair :  Med. See Reslizumab
Ciprofloxacin :  [Cipro] Med. An antibiotic used to treat bacterial infections.
CNS :  [Central Nervous System Vasculitis, Cerebral Vasculitis] Cond.Affects blood vessels in the brain or spine.   More  When not accompanied by other autoimmune diseases it is referred to as Primary Angiitis of the Central Nervous System. (PACNS)
Cogan's Syndrome :  Cond. Variable blood vessel vasculitis. Causes inflammation of the inner ears and eyes. Frequently there is also heart, large blood vessel, nervous system and bowel involvement.  More
Cortef :  Abbr. See Hydrocortisone
Corticosteroid :  Med. Anti-inflammatory synthetic drug used to treat many conditions. Different preparations can be taken orally, injected, inhaled or incorporated into lotions, for topical use. There are many variants. The main oral version used for EGPA is prednisolone but other variants are hydrocortisone which is less potent, methylprednisolone which is similar and can be used as an intramuscular injection or an IV preparation, and dexamethasone which is very potent.
Cortisol :  Term. Steroid hormone produced by the adrenal glands.
Cortisol test :  Test. Quantifies the amount of cortisol in the blood.
Cosyntropin test :  Test. See ACTH Test
Co-trimoxazole :  [Septrin] Med. Treatment of bacterial infections and as a prophylactic against lung infections due to immune deficiency.
Creatine :  Term. Chemical produced in the body which supplies energy to muscles.
Creatinine :  Term. A waste product of creatine, removed by the kidneys. If there is something abnormal with the kidneys, the level of creatinine found in a blood test increases.
CRP :  Abbr. Test. C-reactive protein . Blood test used to detect inflammation.
Cryoglobulinaemic Vasculitis :  [Cryoglobulinemia] Cond.Immune complex, small blood vessel vasculitis. Abnormal antibodies in the blood.  More
Cryoglobulinemia :  Cond. See Cryoglobulinaemic Vasculitis
CT Pulmonary Angiogram :  [CTPA] Test. Uses computer assisted means to view pulmonary arteries and diagnose pulmonary embolism. It is minimally invasive for the patient.
CT Scan :  [CAT Scan] Abbr. Test. Computerised Tomography. Uses many x-ray beams with lower radiation doses, to make 3D images. Tissue can be seen.
Cushing syndrome :  [Hypercortisolism, Moonface] Cond. Often caused by long term treatment with corticosteroids resulting in increased blood cortisol. There are a number of symptoms including a roundening of the face.
Cutaneous leukocytoclastic angiitis :  Cond. See HV
CVA :  Abbr. Cond. Cerebrovascular accident. See Stroke
CVI :  Abbr. Cond. Cerebrovascular insult. See Stroke
CXR :  Abbr. Test. Chest X-Ray
Cyclophosphamide :  [Cytoxan] Med. Immunosuppressive used for steroid sparing.
Cytoxan :  Med. See Cyclophosphamide

D

D-dimer :  Test. A blood test used as a tool, amongst others, to establish whether a patient might have Deep Vein Thrombosis or a Pulmonary Embolism.
Dacryoadenitis :  Cond. Inflammation of the lacrimal glands, often as a result of infection.
Dacryocystitis :  Cond. Inflammation of the lacrimal sac, often as a result of infection.
Deep Vein Thrombosis :  [DVT] Cond. Blood clot in one of the body's deep veins usually a deep leg vein.
Dexamethasone :  [Baycadron] Med. A long-acting systemic corticosteroid.
DEXA scan :  Test. Dual energy X-ray absorptiometry. Measures bone mineral density.
Diuretic :   [Water tablet] Med. Help to remove water and salt by promoting the production of urine. Diuretics can be gentle and long acting or short acting, the latter usually used for oedema.
Drop foot :  [Foot drop] Cond. Muscle weakness or nerve damage causing difficulty to lift the front part of the foot. The foot may also drag on the ground when walking.
Dulera :  Med. See Mometasone/Formoterol
DVT :  Cond. See Deep vein thrombosis.
Dx :  Abbr. Diagnosis.

E

Edema :  Cond. See Oedema
EGD :  Test. See Esophagogastroduodenoscopy
EGPA :  [Eosinophilic Granulomatosis with Polyangiitis, Churg-Strauss Syndrome] Cond. Small blood vessel vasculitis. One of the three types characterised by positive ANCA, though some are ANCA negative.
EMG :  Abbr.Test. See Electromyography
Electromyography :  [EMG] Test. Test to detect the response of muscle cells when activated with an electrical trigger.
Endocarditis :  Cond. Infection of the inner lining of the heart (the endocardium)
Endocrine system :  Term. Collection of glands ; pineal, hypothalamus, pituitary, thyroid, parathyroid, thymus, adrenal, pancreas, ovaries and testes.
Endocrinologist :  Term. Specialist who evaluates and restore hormone imbalances. Works with other specialists in areas such as EGPA where cortico steroids may have impacted the adrenal or other gland functions.
Endocrinology :  Term. Study of actions and disorders of body hormones produced by glands in the endocrine system.
ENT :  Abbr. Ear Nose and Throat. See Otorhinolaryngology
EoE :  [Eosinophilic Esophagitis] Cond. Unwanted presence of eosinophils in the esophagus causes inflammation, leading to problems with swallowing and the gastric system. The majority of sufferers have a family history of allergies or other allergic disorders.  More
Eosinophil :  Term. Type of white blood cell produced in the bone marrow, with specialised functions particularly in relation to the immune system. Can be helpful or cause inflammatory response.
Eosinophilia :  Cond. High levels of eosinophils found in body tissue or blood.
Eosinophilic Esophagitis :  Abbr. See EoE
Eosinophilic phase :  Term. The second phase of EGPA.
Eosinophilic pneumonia :  Cond. Eosinophils when accumulated in the lung cause disruption of the oxygen extraction process causing inflammation. Diagnosis normally involves a physical examination blood tests, x-rays or CT scan. There are a number of different types of Eosinophilic pneumonia.
Esophagogastroduodenoscopy :  [EGD] Test. Endoscopic examination of the lining of the esophagus, stomach, and first part of the small intestine.
ESR :  [SED rate] Abbr. Test. Erythrocyte Sedimentation Rate. Blood test used to detect inflammation.
Etiology :  Term. See Aetiology
Extravascular :  Term. Outside the blood or lymph vessels.

F

Flixotide :  Med. See Fluticasone
Fluoroscopy :  Test. Uses X-rays to see moving images of internal organs.
Fluticasone :  [Flixotide] Med. Inhaler. Asthma maintenance, corticosteroid.
Foot drop :  Cond. See Drop foot
Furosemide :  Med. A loop diuretic (water pill) used to treat Oedema

G

Gabapentin :  Med. Used to treat peripheral nerve pain (hands, legs or feet)
Gastroenterologist :  Term. Specialist who investigates, diagnoses and treats gastrointestinal and hepatological diseases.
Gastroenterology :  Term. A branch of medicine focused on the digestive system and its disorders.
Gastrointestinal system:  Term. The system that processes food, from the oral cavity, oesophagus, stomach, small intestine, large intestine, rectum to the anus. Accessory organs include the salivary glands, pancreas, liver and gall bladder.
Gastroparesis :  Cond. Chronic condition in which the stomach cannot empty itself in the normal way.   More
GCA :  [Giant Cell Arteritis, Temporal Arteritis] Cond. Large blood vessel vasculitis. Most commonly the blood vessels in the temple are affected.  More
Giant Cell Arteritis :  Cond. See GCA
Glands :  Med. Organs that secrete hormones into the bloodstream controlling food adsorbtion, blood regulation and composition, reproduction and reaction to emergencies. The adrenal gland for example, produces cortisol which is a steroid.
Glomerulonephritis :  Cond. Damage to the kidney filters (the glomeruli) caused by immune system attack.
Glucocorticoid :  Term. Steroid hormone, produced by the adrenal gland.
Goodpasture's disease :  Cond. See Anti-GBM
GPA :  [Granulomatosis with Polyangiitis, Wegener's Granulomatosis] Cond.Small blood vessel vasculitis. One of the three types characterised by positive ANCA, though some are ANCA negative.   More
Granuloma :  Term. A local, nodular area of tissue inflammation, normally in the lungs.
Granulomatosis with Polyangiitis :  Cond. See GPA

H

Hay Fever :  Term. See Allergic rhinitis
Hematuria :  Term.Red blood cells detected in the urine.
Henoch-Schönlein :  Cond. See IgA Vasculitis
Hepatology :  Term. Branch of medicine closely related to gastroenterology but focussed on the liver, gall bladder, biliary tree, and pancreas.
Hepatologist :  Term. Specialist in Hepatology.
HES :  [Hypereosinophilic syndrome] Cond. A type of eosinophilia, associated with persistent high blood eosinophil count and consequent organ damage, if untreated. Diagnosis is particularly challenging, for example in distinguishing between eosinophilia with organ involvement and that associated with a systemic vasculitis. More
HUV :  [Hypocomplementemic urticarial vasculitis] Cond. Immune complex, small blood vessel vasculitis. Affects skin, joints, lungs and stomach. One of the subtypes of Urticarial vasculitis.
HUVS :  [Hypocomplementemic urticarial vasculitis syndrome, McDuffie syndrome, antiC1q vasculitis] Cond. Immune complex, small blood vessel vasculitis. The rarest and most severe form of Urticarial Vasculitis.
HV :  [Hypersensitivity vasculitis, Cutaneous leukocytoclastic angiitis] Cond. A single organ vasculitis. Most commonly only the skin is affected.
Hydrocortisone :  [Cortef] Med. A short acting systemic corticosteroid.
Hypercortisolism :  Cond. See Cushing syndrome
Hypereosinophilic syndrome :  Cond. See HES
Hypersensitivity vasculitis :  Cond. See HV
Hypocomplementemic urticarial vasculitis :  Cond. See HUV
Hypocomplementemic urticarial vasculitis syndrome :  Cond. See HUVS
Hypokalemia :  Cond. Low potassium concentration in the blood.

I

IgA Vasculitis :  [Henoch-Schönlein] Cond.Immune complex, small blood vessel vasculitis. Affects skin, joints, kidneys and bowel.  More
Immunosuppressant :  Med. Reduces the strength of the body's immune system.
Immunoglobulin :  Term. See Antibody
Immunologist :  Term. Studies and treats patients with immune system disorders.
Immunology :  Term. Concerned with the function of the immune system.
Infarction :  Term. Obstruction of tissue blood supply causing tissue death due lack of oxygen.
Inflammation :  Term. Reaction to infection or injury, characterised by redness, swelling, heat and pain.
IS :  Abbr. Med. Immunosuppressant.
INR :  Abbr. Test. International Normalised Ratio. Blood clotting time test used to check the effects of anticoagulants such as warfarin.
Imuran :  Med. See Azathioprine
Isolated Aortitis :  Cond. A single organ vasculitis affecting the aorta, a large vessel connected to the heart. More

J

J :  J
J :  J

K

Kawasaki Disease :  Cond. See KD
KD :  [Kawasaki Disease] Cond. Medium blood vessel vasculitis. The coronary arteries are commonly affected. More

L

Lacrimal glands :  Term. Situated above each eye they secrete aqueous fluid (proteins, electrolytes and water) into the eye becoming a component of the tear film and ultimately draining via the nose.
Lacrimal inflammation :  Cond. The lacrimal gland can be inflamed by some autoimmune diseases typically Sjögren's syndrome.
Lacrimal sac :  Term. Part of the structure that transports fluid from the eye to the nose.
Lemtrada :  Med. See Alemtuzumab
Leukotriene receptor antagonist :  Term. Class of non-steroidal, anti-inflammatory drug widely prescribed for the management of asthma and allergic rhinitis symptoms. Sometimes used when inhaled steroids fail to control asthma. Blocks the action of substances (Leukotrienes) that cause the symptoms.
Leukotrienes :  Term. Inflammatory molecules produced in leukocytes released during an asthma attack. Eosinophils, also produce leukotrienes causing longer term chronic asthma.
Loop Diuretic :  Med. Acts on a part of the kidney called the 'Loop of Henle' to inhibit sodium and chloride reabsorption.
Lower GI series :  Test. See Barium enema
Lupus :  Cond. See SLE  for the most severe form of the condition.
Lymphocyte :  Term. White blood cell type generated by the immune system to defend against antigens. There are three types, B cells, T cells (Immune response specialists) and natural killer cells.
Lyrica :  Med. See Pregabalin

M

McDuffie syndrome :  Cond. See HUVS
Medrol :  Abbr. See Methylprednisolone
Mediastinum :  Term. An area principally containing the heart, trachea and and great vessels.
Mepolizumab :  [Nucala] Med. Treatment for severe eosinophilic asthma in adult patients. (IgG1 monoclonal antibody specific for IL-5) Investigations for EGPA still ongoing.
Mercaptopurine :  Med. See 6-Mercaptopurine
Methotrexate :  [Rheumatrex, Trexall] Med. Immunosuppressive used for steroid sparing.
Methylprednisolone :  [Medrol] Med. Intermediate acting corticosteroid similar to Prednisone. Can be given orally by intramuscular injection or an IV preparation.
Microscopic Polyangiitis :  Cond. See MPA
Mononeuropathy :  Term. Neuropathy affecting only one nerve in the peripheral nervous system.
Mononeuropathy multiplex :  Term. Neuropathy affecting two or more nerves in the peripheral nervous system.Non symmetrical locations.
Montelukast :  [Singulair] Med. Long term prevention of allergic rhinitis, breathing difficulties during exercise and asthma. A leukotriene receptor antagonist.
Mometasone/Formoterol :  [Dulera, Zenhale] Med. Corticosteroid and long acting bronchodilator in a single inhaler.
Moonface :  Cond. See Cushing syndrome
MPA :  [Microscopic Polyangiitis] Cond. Small blood vessel vasculitis. One of the three types characterised by positive ANCA, though some are ANCA negative.  More
MRA Scan :  Abbr. Test. Magnetic Resonance Angiogram. Type of MRI scanner for the heart and associated blood vessels.
MRI Scan :  Abbr. Test. Magnetic Resonance Imaging. Uses magnets, no radiation. Very detailed images especially for soft tissues and even nerves.
Myalgia :  Term.Muscle pain.
Myfenax :  Med. See Mycophenelate mofetil
Mycophenolate mofetil :  [Cellcept, Myfenax] Med. Immunosuppressive used for steroid sparing.

N

Nasal polyps :  Term. Inflammatory growth in the nasal lining that occurs inside the nasal passages and sinuses.
Necrosis :  Term. Death of body cells due to disease, injury or blood supply failure.
Nephrologist :  Term. Specialist in nephrology.
Nephrology :  Term. lnvestigation, diagnosis and medical treatment of the kidneys.
Neuropathy :  Cond. Nerve damage, with inflammation.
Normocomplementemic Urticarial Vasculitis :  Cond. See NUV
Nucala :  Med. See Mepolizumab
NUV :  [Normocomplementemic Urticarial Vasculitis] Cond. Immune complex, small blood vessel vasculitis. Affects skin. Generally the least severe form of Urticarial Vasculitis.

O

Oedema :  [Edema] Cond. Fluid build up, commonly in legs and ankles. There are different types of Oedema and medical investigation is normally advised.
Omalizumab :  [Zyflo] Med. Injection. Moderate to severe asthma treatment, when asthma not responding to corticosteroids.
Ondansetron :  [Zofran, Zuplenz] Med. Blocks the action of serotonin that can trigger chemotherapy induced nausea and vomiting.
Orbital pseudotumour :  Cond. Swelling of tissue behind the eye.
Osteopenia :  Term. Bone mineral density is lower than normal and could suggest progression to osteoporosis.
Osteoporosis :  Term. Bone mineral density is much lower than normal making bones prone to fracture. Continued use of corticosteroids is one cause.
Osteopathic Frontal Sinus Obliteration Surgery :  Term. Surgery to eliminate the frontal sinuses in order to prevent chronic infection.
Otorhinolaryngologist :  [ENT Doctor]Term. Specialist who investigates, diagnoses and treats ear, nose, and throat and corresponding head and neck issues.
Otorhinolaryngology :  [ENT]Term. Branch of medicine dealing with the ear, nose, and throat and corresponding head and neck issues.

P

PACNS :  [Primary Angiitis of the Central Nervous System] Cond. Affects blood vessels in the brain or spine. When accompanied with other autoimmune diseases it is referred to as Central Nervous System Vasculitis (CNS)
PAN :  [Polyarteritis Nodosa] Cond. Medium blood vessel vasculitis. Most commonly the muscles, joints, intestines, nerves and skin are affected.  More
Pancreatitis :  Cond. Inflammation of the pancreas.
Pericardial effusion :  [Cardiac effusion] Cond. Excessive build up of fluid between the layers (pericardium) around the heart.
Pericardial tamponade :  [Cardiac tamponade] Cond. An acute type of pericardial effusion
Pericardiectomy :  Term. The removal of a portion or all of the pericardium outer layer.
Pericardium :  Term. The double layered membrane that protects the heart from infection and other sources of disease.
Peripheral neuropathy :  Cond. Damage to the peripheral nervous system, the nerves outside the brain and spinal cord (central nervous system).
PFT :  Abbr. Pulmonary function test.
Plaquenil :  Med. An anti-malaria drug also used as an immunosuppressant alternative.
Pleural cavity :  Abbr. The fluid filled gap between the two thin membranes (pleura) that line and surround the lungs. It provides lubrication to the lungs during breathing.
Pneumonia :  Cond. Inflammation of the lung tissue, normally caused by an infection. A productive cough, fever and difficulty breathing are typical symptoms.
Polyarteritis Nodosa :  Cond. See PAN
Polyps :  Cond. Growths of tissue that can be found in any organ that has blood vessels. Nasal growths are typical in EGPA.
Prednisolone :  Med. Synthetic glucocorticoid, used to treat inflammatory and auto-immune conditions by suppressing the immune system. Patients with liver problems often use this as they cannot metabolise prednisone into prednisolone. Intermediate acting systemic corticosteroid.
Prednisone :  Med. Synthetic glucocorticoid, used to treat inflammatory and auto-immune conditions by suppressing the immune system. The liver converts prednisone into prednisolone, the active drug which is a steroid.
Pregabalin :  [Lyrica] Med. Used to treat peripheral nerve pain (hands, legs or feet)
Primary Angiitis of the Central Nervous System :  Cond. See PACNS
Prodromal phase :  Term. Early symptoms that might indicate the start and first phase of EGPA.
Prophylactic :  Med. Used proactively to prevent disease.
Pseudotumour :  Cond. Swelling resembling a tumour; it can result from inflammation or be due to accumulation of fluid.
Pulmonologist :  Term. See Respiratory Physician
Pulmonary Embolism :  [PE] Cond. Blockage (usually a blood clot) in the pulmonary artery, the blood vessel that carries blood from the heart to the lungs.
Pulmonary function test :  Test. Measures lung expansion, contraction and efficiency of oxygen/carbon dioxide exchange between blood and air within the lungs.
Purinethol :  Med. See 6-Mercaptopurine

Q

Quidditch :  A sport with two teams on broomsticks, using a Quaffle, two Bludgers, and a Golden Snitch.

R

Ranitidine :  Med. Used to treat and prevent ulcers in the stomach and intestines.
Red Skin Syndrome :  [RSS, Topical Steroid Addiction (TSA),Steroid Addiction, Corticosteroid Addiction,Topical Corticosteroid Addiction (TCS Addiction),Steroid Addiction Syndrome, Topical Corticosteroid Withdrawal (TCS Withdrawal), Topical Corticosteroid Withdrawal Syndrome (TCS Withdrawal Syndrome),Topical Steroid Damaged Facies (TSDF), Red Burning Skin Syndrome Steroid Dermatitis, Steroid-Induced Dermatitis (SID), Steroid Dermatitis Resembling Rosacea, Steroid- Induced Rosacea-like Dermatitis (SIRD), Steroid-induced Rosacea-like Eruption, Topical Corticosteroid-Induced Rosacea-like Dermatitis (TCIRD)] Term..A debilitating condition that can arise from the use of topical steroids to treat a skin problem.
Respiratory Physician :  [Pulmonologist, Respirologist] Term. Focus on lung diseases, including those caused by allergic reactions, vascular and inflammatory problems often associated with asthma, a common precursor to EGPA. They work with other specialists and dedicated laboratories to arrive at more complex diagnosis.
Respiratory tract :  Term. Air passage formed by the mouth, nose, throat, and lungs.
Respirologist :  Term. See Respiratory Physician
Retrobulbar :  Term. Behind the eyeball
Reslizumab :  [Cinqair] Med. Humanised monoclonal antibody to interleukin-5 for treatment of severe asthma in adults.
Rheumatoid Vasculitis :  Cond. See RV
Rheumatrex :  Med. See Methotrexate
Rhinitis :  Cond. Inflammation of the mucous membrane of the nose
Rituximab :  [Rituxan] Med. Immunosuppressive used for steroid sparing.
Rituxan :  Med. See Rituximab
RV :  [Rheumatoid Vasculitis] Cond.Small and medium-sized vessel systemic vasculitis. A complication of rheumatoid arthritis which commonly affects the skin and the nerves.  More

S

Salbutamol :  [Ventolin] Med. Inhaler. Asthma reliever. Widens airways to lungs so that air can flow more freely.
Sando-K :  Med. Potassium supplement for low blood potassium levels.
SED Rate :  Test. Blood. See ESR
Septrin :  Med. See Co-trimoxazole
Sequela :  Term. A new condition consequent to a previous condition, which may occur some years later.
Serum :  Term. Component of blood containing no cells or clotting factors. A liquid containing electrolytes and proteins, obtained after allowing blood clotting.
Serum urea :  Term. Ammonia created by the liver is broken down into urea which is filtered by the Kidneys and excreted in urine and sweat. Some goes into the bloodstream as serum urea.
Sialadenitis :  Cond. Inflammation of the salivary glands.
Singulair :  Med. See Montelukast
Sjögren's syndrome :  Cond. Autoimmune disorder,affecting glands that secrete fluid, such as the tear and saliva glands.
SLE :  [Systemic Lupus Erythematosus] Cond. Small vessel systemic vasculitis. The most severe form of lupus, which can affect skin, joints and internal organs.  More
Spironolactone :  Med. Potassium sparing diuretic (water pill) used to treat Oedema.
Stroke :  [CVA, CVI, Brainattack] In the brain, restricted blood flow results in cell death.
Synacthen test :  Test. See ACTH Test
Systemic :  Term. Affecting the body as a whole.
Systemic Lupus Erythematosus :  Cond. See SLE

T

TA :  [Takayasu's Arteritis] Cond. Large blood vessel vasculitis. Most commonly the aorta and the pulmonary artery are affected.   More
Takayasu's Arteritis :  Cond. See TA
Temporal Arteritis :  Cond. See GCA
Tetracosactide test :  Test. See ACTH Test
Thoracic cavity :  [Chest cavity] Term. Includes everything between the neck and the diaphragm princially the mediastinum and pleural cavities.
Thoracoscopy :  Term. The internal examination, biopsy, and/or resection of disease or masses within the thoracic cavity.
Thromboangiitis Obliterans :  Cond. See Buerger's Disease
Trexall :  Med. See Methotrexate
Trochleitis :  Cond. Normally affects a single eye, with swelling of the oblique tendon and surrounding tissues controlling eye movement. May be associated with with an inflammatory condition. Pain is experienced near the nose and inner eyebrow. Ultrasound is used as one diagnostic tool.
Tissue eosinophilia :  Cond. High levels of eosinophils in body tissue, rather than blood, at the site of an infection or inflammation.

U

Upper GI series :  Test. See Barium swallow
Urticarial Vasculitis :  Cond. Immune complex, small blood vessel vasculitis. Splits into 3 subtypes HUVS, NUV and HUVMore
UTI :  Abbr. Cond. Urinary tract infection.

V

Vasculitic phase :  Term. The third and final phase of EGPA.
Vasculitus :  Cond. Inflammation of the blood vessels. In EGPA, mainly the small blood vessels.
Venous Thromboembolism :  [VTE] Cond. Collective name for Deep Vein Thrombosis and Pulmonary Embolism.
Ventolin :  Med. See Salbutamol.
Vital organs :  Term.The main organs needed to sustain life.
VTE :  Abbr. See Venous Thromboembolism.

W

Water tablet :  Med. See Diuretic
Wegener's Granulomatosis :  Cond. See GPA

X

X-Rays :  Test. Used to take grey scale images. They are best for looking at bone.
Xolair :  Med. See Omalizumab

Y

Y :  Y
Y :  Y

Z

Zafirlukast :  [Accolate] Med. Long term prevention of allergic rhinitis, breathing difficulties during exercise and asthma. A leukotriene receptor antagonist.
Zenhale :  Med. See Mometasone/Formoterol
Zileuton :  [Zyflo] Med. Tablet. Asthma maintenance, inhibits leukotrienes.
Zofran :  Med. See Ondansetron
Zuplenz :  Med. See Ondansetron
Zyflo :  Med. See Zileuton

Greek

β-2 agonist :  Med. See Beta agonist

Other

6-Mercaptopurine :  [Mercaptopurine, Purinethol] Med. Immunosuppressant. Not commonly used for EGPA.
Other :  Other

Glossary help.

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Objective. To convey the rough meaning of a word or phrase in common use for EGPA

Important. Where medication is defined, the typical use for EGPA treatment is sometimes quoted. There are often many other uses for various medications not mentioned here. Do not take any medication soley on the basis of the any comment in this glossary. All medication has very specific manufacturers instructions. Many have unwanted side effects and can interact with other drugs to detrimental effect. This glossary does not cover or advise on any such potential effects or interactions.

Never change your medication regime except under advise of your doctor.

Meanings.
Abbr. = Abbreviation.
Med. = Medication or drug.
Cond. = Medical condition.
Test. = Medical test.
Term. = Medical term.

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